Should the Urologist Demarcate the Surgical Specimen after Radical Prostatectomy

• Main Authors: Rodrigo B Abdo, Ana P Drummond-Lage, Daniela Savi, Adilson Savi, Alberto J A Wainstein
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2019-01-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: cancer; pathology; prostatic cancer
• Online Access: https://jcdr.net/articles/PDF/12440/38197_CE[Ra1]_F(SL)_PF1(AJ_SHU)_PFA(AJ_SHU)_PN(SL).pdf
• ISSN: 2249-782X; 0973-709X

Introduction: Although the literature about prostate cancer is vast in tracking discussion about diagnosis and treatment of prostate cancer, there are few publications about the best form of surgical specimen processing of radical prostatectomy. After the surgery, the urologist limits his responsibility to forward surgical specimen for analysis. Aim: To evaluate if the urologist manipulation trying to locate and demarcate suspicious areas of a tumour can improve the microscopic examination. Materials and Methods: Twenty surgical specimens of radical prostatectomy performed in patients with localised prostate cancer were macroscopically analysed by a single urologist and suspicious areas for cancer were marked with surgical thread. Later these areas were correlated with the findings in the microscopic study. Results: It was observed that in 75.8% of cases, there was a positive correlation between the pit and the clinical pathology report on the cancer presence, and in 50% of cases, the demarcated areas corresponded to the area of most considerable extent of cancer throughout the prostate. Conclusion: The demarcation of cancer suspected areas by Urologist, in surgical specimens from radical prostatectomy may provide additional information to the pathologist, directing the histopathological analysis of the prostate to the areas with more significant tumour extension compared to the other sections.