BACE1 inhibitory activity of fungal endophytic extracts from Malaysian medicinal plants

<p>Abstract</p> <p>Background</p> <p>BACE1 was found to be the major β-secretase in neurons and its appearance and activity were found to be elevated in the brains of AD patients. Fungal endophytic extracts for BACE1 inhibitory activity and cytotoxicity against PC-12 (a...

Full description

Bibliographic Details
Main Authors: Cole Anthony LJ, Majeed Abu, Lim Siong, James Richard, Harun Azzeme, Ramasamy Kalavathy
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Complementary and Alternative Medicine
Online Access:http://www.biomedcentral.com/1472-6882/11/79