Anti-UVC Irradiation and Metal Chelation Properties of 6-Benzoyl-5,7-dihydroxy-4-phenyl-chromen-2-one: An Implications for Anti-Cataract Agent

Anti-UVC Irradiation and Metal Chelation Properties of 6-Benzoyl-5,7-dihydroxy-4-phenyl-chromen-2-one: An Implications for Anti-Cataract Agent

Coumarin derivative 1, 5,7-dihydroxy-6-(3-methyl-1-butyryl)-4-phenyl-chromen-2-one, has been reported to possess radical scavenging activity and DNA protection. We have synthesized a series of coumarins with structural modifications at positions C4, C5, C6 and C7 and evaluated them for their anti-UV...

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Bibliographic Details
Main Authors: Jiahn-Haur Liao, Shih-Hsiung Wu, Zih-You Huang, Mei-Hsiang Lin, Chi-Hsien Huang, Po-Hung Chiang, Tzu-Hua Wu, Yi-Shiang Huang, Feng-Lin Hsu
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:International Journal of Molecular Sciences
Subjects:
irradiation
anti-cataract
coumarin
γ-crystallin
iron-chelation
Online Access:http://www.mdpi.com/1422-0067/12/10/7059/

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