Heart Failure With Preserved Ejection Fraction: A Review of Cardiac and Noncardiac Pathophysiology

Heart Failure With Preserved Ejection Fraction: A Review of Cardiac and Noncardiac Pathophysiology

Heart failure with preserved ejection fraction (HFpEF) is one of the largest unmet clinical needs in 21st-century cardiology. It is a complex disorder resulting from the influence of several comorbidities on the endothelium. A derangement in nitric oxide bioavailability leads to an intricate web of...

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Bibliographic Details
Main Authors: Andreas B. Gevaert, Jente R. A. Boen, Vincent F. Segers, Emeline M. Van Craenenbroeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Physiology
Subjects:
heart failure
pathophysiology
comorbidities
endothelium
microRNA
iron deficiency
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00638/full

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