Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats

Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats

The maladaptive response of aged microglia to surgery and consequent neuroinflammation plays a key pathogenic role in postoperative cognitive dysfunction (POCD). Here, we assessed the preventive effect of resveratrol (RESV) for POCD in aged rats. The emulsified form of RESV (e-RESV) was selected to...

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Bibliographic Details
Main Authors: Fabricio M. Locatelli, Takashi Kawano, Hideki Iwata, Bun Aoyama, Satoru Eguchi, Atsushi Nishigaki, Daiki Yamanaka, Hiroki Tateiwa, Marie Shigematsu-Locatelli, Masataka Yokoyama
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861318301555

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