Genetic Polymorphisms and Platinum-Based Chemotherapy-Induced Toxicities in Patients With Lung Cancer: A Systematic Review and Meta-Analysis

Genetic Polymorphisms and Platinum-Based Chemotherapy-Induced Toxicities in Patients With Lung Cancer: A Systematic Review and Meta-Analysis

Background: Platinum-based agents, including cisplatin, carboplatin, and oxaliplatin, are indispensable for the treatment of lung cancer. The development of toxicity frequently necessitates dose reduction or discontinuation of therapy, despite the clinical response. Pharmacogenomics studies were rev...

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Bibliographic Details
Main Authors: Wenhui Liu, Ying Wang, Jianquan Luo, Haiyan Yuan, Zhiying Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
platinum
pharmacogenomics
toxicity
individual difference
meta-analysis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01573/full

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