Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs

In six dogs, experimental model of osteoarthritis (OA) was reproduced by intraarticular injection of sodium monoiodoacetate (MIA) in left stifle joints. Contralateral joints served as control. The clinical status and some goniometric parameters were monitored before MIA introduction and at post inje...

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Main Author: N V Goranov
Format: Article
Language:English
Published: Veterinary World 2012-06-01
Series:Veterinary World
Subjects:
Online Access:http://www.scopemed.org/mnstemps/2/2-1323941254.pdf
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spelling doaj-b0c756eeaf8e4c8891a9c466873162382021-08-02T07:03:31ZengVeterinary WorldVeterinary World0972-89882231-09162012-06-0153.000138144Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs N V GoranovIn six dogs, experimental model of osteoarthritis (OA) was reproduced by intraarticular injection of sodium monoiodoacetate (MIA) in left stifle joints. Contralateral joints served as control. The clinical status and some goniometric parameters were monitored before MIA introduction and at post injection days 30, 60 and 105. The results showed convincingly that the used experimental chemical OA model reproduced successfully the disease in canine stifle joints. The studied clinical indices correlated with the severity of disease. [Vet. World 2012; 5(3.000): 138-144]http://www.scopemed.org/mnstemps/2/2-1323941254.pdfdogsstifle jointsodium monoiodoacetateosteoarthritis
collection DOAJ
language English
format Article
sources DOAJ
author N V Goranov
spellingShingle N V Goranov
Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs
Veterinary World
dogs
stifle joint
sodium monoiodoacetate
osteoarthritis
author_facet N V Goranov
author_sort N V Goranov
title Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs
title_short Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs
title_full Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs
title_fullStr Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs
title_full_unstemmed Clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs
title_sort clinical changes in sodium monoiodoacetate–induced stifle osteoarthritis model in dogs
publisher Veterinary World
series Veterinary World
issn 0972-8988
2231-0916
publishDate 2012-06-01
description In six dogs, experimental model of osteoarthritis (OA) was reproduced by intraarticular injection of sodium monoiodoacetate (MIA) in left stifle joints. Contralateral joints served as control. The clinical status and some goniometric parameters were monitored before MIA introduction and at post injection days 30, 60 and 105. The results showed convincingly that the used experimental chemical OA model reproduced successfully the disease in canine stifle joints. The studied clinical indices correlated with the severity of disease. [Vet. World 2012; 5(3.000): 138-144]
topic dogs
stifle joint
sodium monoiodoacetate
osteoarthritis
url http://www.scopemed.org/mnstemps/2/2-1323941254.pdf
work_keys_str_mv AT nvgoranov clinicalchangesinsodiummonoiodoacetateamp150inducedstifleosteoarthritismodelindogs
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