New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity

New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity

Two new benzoic acid derivatives: 1-p-hydroxy benzoyl-3-palmitoyl glycerol (1) and 6 -p-hydroxy benzoyl daucosterol (2), along with scutellarein-6-methyl ether (3), quercetin (4), and rutin (5) had been separated from Cassia italica (Fabaceae) aerial parts from EtOAc fraction. Their characterisation...

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Bibliographic Details
Main Authors: Rwaida A. Al-Haidari, Mai M. Al-Oqail
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Saudi Pharmaceutical Journal
Subjects:
Cassia italic
Fabaceae
Diglyceride derivative
Daucosterol derivative
Antioxidant
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420301663
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spelling doaj-b0b587eb42b644d8b96e02a135f7b0f82020-11-25T03:43:33ZengElsevierSaudi Pharmaceutical Journal1319-01642020-09-0128911121117New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activityRwaida A. Al-Haidari0Mai M. Al-Oqail1Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, Al Madinah Al Munawwarah 30078, Saudi ArabiaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia; Corresponding author.Two new benzoic acid derivatives: 1-p-hydroxy benzoyl-3-palmitoyl glycerol (1) and 6 -p-hydroxy benzoyl daucosterol (2), along with scutellarein-6-methyl ether (3), quercetin (4), and rutin (5) had been separated from Cassia italica (Fabaceae) aerial parts from EtOAc fraction. Their characterisation was accomplished by various spectroscopic techniques and by comparing with the published data. The Ethyl acetate (EtOAc) fraction and compounds 1–5 had been assessed for their antioxidant potential utilizing DPPH assay. They had significant antioxidant capacities with activity ranged from 19.7 to 95.8%, in comparison to butylated hydroxyanisole (BHA) (93.8%). These findings could provide a further evidence to support the traditional use of C. italica for the treatment of chronic or degenerative illnesses.http://www.sciencedirect.com/science/article/pii/S1319016420301663Cassia italicFabaceaeDiglyceride derivativeDaucosterol derivativeAntioxidant
collection DOAJ
language English
format Article
sources DOAJ
author Rwaida A. Al-Haidari
Mai M. Al-Oqail
spellingShingle Rwaida A. Al-Haidari
Mai M. Al-Oqail
New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity
Saudi Pharmaceutical Journal
Cassia italic
Fabaceae
Diglyceride derivative
Daucosterol derivative
Antioxidant
author_facet Rwaida A. Al-Haidari
Mai M. Al-Oqail
author_sort Rwaida A. Al-Haidari
title New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity
title_short New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity
title_full New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity
title_fullStr New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity
title_full_unstemmed New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity
title_sort new benzoic acid derivatives from cassia italica growing in saudi arabia and their antioxidant activity
publisher Elsevier
series Saudi Pharmaceutical Journal
issn 1319-0164
publishDate 2020-09-01
description Two new benzoic acid derivatives: 1-p-hydroxy benzoyl-3-palmitoyl glycerol (1) and 6 -p-hydroxy benzoyl daucosterol (2), along with scutellarein-6-methyl ether (3), quercetin (4), and rutin (5) had been separated from Cassia italica (Fabaceae) aerial parts from EtOAc fraction. Their characterisation was accomplished by various spectroscopic techniques and by comparing with the published data. The Ethyl acetate (EtOAc) fraction and compounds 1–5 had been assessed for their antioxidant potential utilizing DPPH assay. They had significant antioxidant capacities with activity ranged from 19.7 to 95.8%, in comparison to butylated hydroxyanisole (BHA) (93.8%). These findings could provide a further evidence to support the traditional use of C. italica for the treatment of chronic or degenerative illnesses.
topic Cassia italic
Fabaceae
Diglyceride derivative
Daucosterol derivative
Antioxidant
url http://www.sciencedirect.com/science/article/pii/S1319016420301663
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AT maimaloqail newbenzoicacidderivativesfromcassiaitalicagrowinginsaudiarabiaandtheirantioxidantactivity
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