Quantitation of CDH1 promoter methylation in formalin-fixed paraffin-embedded tissues of breast cancer patients using differential high resolution melting analysis

Quantitation of CDH1 promoter methylation in formalin-fixed paraffin-embedded tissues of breast cancer patients using differential high resolution melting analysis

Background: E-cadherin (CDH1) plays an important role in cell–cell adhesion of epithelial tissues. Loss of E-cadherin expression can lead to loss of tissue integrity, metastasis, and cancer progression. Also loss of E-cadherin expression might be related to aberrant promoter methylation of the CDH1...

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Bibliographic Details
Main Authors: Mojgan Naghitorabi, Javad Mohammadi-Asl, Hamid Mir Mohammad Sadeghi, Mohammad Rabbani, Abbas Jafarian-Dehkordi, Shaghayegh Haghjooy Javanmard
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Advanced Biomedical Research
Subjects:
Breast cancer
CDH1
FFPE
high resolution melting analysis
promoter methylation
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2016;volume=5;issue=1;spage=91;epage=91;aulast=Naghitorabi

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