Salidroside protects endothelial cells against LPS-induced inflammatory injury by inhibiting NLRP3 and enhancing autophagy

Salidroside protects endothelial cells against LPS-induced inflammatory injury by inhibiting NLRP3 and enhancing autophagy

Abstract Background Salidroside (SAL) is a bioactive compound extracted from Rhodiola rosea with various biological properties. This study was designed to explore the functions of SAL on the endothelial damage induced by lipopolysaccharide (LPS) and its related mechanisms. Methods Human umbilical ve...

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Bibliographic Details
Main Authors: Lijiao You, Di Zhang, Huan Geng, Fangyuan Sun, Ming Lei
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Sepsis
Salidroside (SAL)
Human umbilical vein endothelial cells (HUVECs)
Lipopolysaccharide (LPS)
Apoptosis
Inflammation
Online Access:https://doi.org/10.1186/s12906-021-03307-0

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