CCR4+ Skin-Tropic Phenotype as a Feature of Central Memory CD8+ T Cells in Healthy Subjects and Psoriasis Patients

CCR4+ Skin-Tropic Phenotype as a Feature of Central Memory CD8+ T Cells in Healthy Subjects and Psoriasis Patients

The chemokine receptor CCR4 has emerged as a skin-homing molecule important for the migration of T cells from the blood to the dermis. From our previous data on psoriasis patients, CCR4+ memory T cells emerged as a putative recirculating population between skin and blood. Here we focused our attenti...

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Bibliographic Details
Main Authors: Fabio Casciano, Marco Diani, Andrea Altomare, Francesca Granucci, Paola Secchiero, Giuseppe Banfi, Eva Reali
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
psoriatic disease
effector memory
central memory
tissue immunosurveillance
skin
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00529/full

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