Exercise Attenuates Brain Aging by Rescuing Down-Regulated Wnt/β-Catenin Signaling in Aged Rats

Down-regulated Wnt signaling is involved in brain aging with declined cognitive capacity due to its modulation on neuronal function and synaptic plasticity. However, the molecular mechanisms are still unclear. In the present study, the naturally aged rat model was established by feeding rats from 6...

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Bibliographic Details
Main Authors: Dandan Chen, Ying Zhang, Meng Zhang, Jingru Chang, Zhenzhong Zeng, Xianjuan Kou, Ning Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Wnt
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00105/full