Molecular neural crest cell markers enable discrimination of organophosphates in the murine cardiac embryonic stem cell test

Molecular neural crest cell markers enable discrimination of organophosphates in the murine cardiac embryonic stem cell test

The cardiac embryonic stem cell test (ESTc) originally used the differentiation of beating cardiomyocytes for embryotoxicity screenings of compounds. However, the ESTc consists of a heterogeneous cell population, including neural crest (NC) cells, which are important contributors to heart developmen...

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Bibliographic Details
Main Authors: R.H. Mennen, N. Hallmark, M. Pallardy, R. Bars, H. Tinwell, A.H. Piersma
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Cardiac embryonic stem cell test
Neural crest
Developmental toxicology
Organophosphates
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021001438

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