High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy.

High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy.

Immunotherapy based on natural killer (NK) cell infusions is a potential adjuvant treatment for many cancers. Such therapeutic application in humans requires large numbers of functional NK cells that have been selected and expanded using clinical grade protocols. We established an extremely efficien...

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Bibliographic Details
Main Authors: Jan Spanholtz, Marleen Tordoir, Diana Eissens, Frank Preijers, Arnold van der Meer, Irma Joosten, Nicolaas Schaap, Theo M de Witte, Harry Dolstra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2821405?pdf=render

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