Insights into the structure and architecture of the CCR4-NOT complex

Insights into the structure and architecture of the CCR4-NOT complex

The CCR4-NOT complex is a highly conserved, multifunctional machinery with a general role in controlling mRNA metabolism. It has been implicated in a number of different aspects of mRNA and protein expression, including mRNA degradation, transcription initiation and elongation, ubiquitination, and p...

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Bibliographic Details
Main Authors: Kun eXu, Yuwei eBai, Aili eZhang, Qionglin eZhang, Mark Gerrard Bartlam
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Genetics
Subjects:
protein structure
Ccr4-Not complex
mRNA decay
deadenylation
poly(A)
NOT module
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00137/full

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