tRNA Modification Detection Using Graphene Nanopores: A Simulation Study

tRNA Modification Detection Using Graphene Nanopores: A Simulation Study

There are over 100 enzyme-catalyzed modifications on transfer RNA (tRNA) molecules. The levels and identity of wobble uridine (U) modifications are affected by environmental conditions and diseased states, making wobble U detection a potential biomarker for exposures and pathological conditions. The...

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Bibliographic Details
Main Authors: Khadijah Onanuga, Thomas J. Begley, Alan A. Chen, Srivathsan V. Ranganathan
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Biomolecules
Subjects:
tRNA modification
graphene
nanopore
wobble uridine
Online Access:https://www.mdpi.com/2218-273X/7/3/65

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