CoQ10 enhances PGC1α and increases expression of mitochondrial antioxidant proteins in chronically ischemic swine myocardium

CoQ10 enhances PGC1α and increases expression of mitochondrial antioxidant proteins in chronically ischemic swine myocardium

Abstract Background Expression of mitochondrial proteins is reduced within hibernating myocardium (HM). It is unclear whether dietary supplementation with CoQ10 can increase expression of mitochondrial electron transport chain (ETC) and antioxidant proteins within this tissue. In a swine model of HM...

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Bibliographic Details
Main Authors: Laura Hocum Stone, Erin Chappuis, Christin Wright, Rosemary F. Kelly, Edward O. McFalls
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Nutrition & Metabolism
Subjects:
Hibernating myocardium
CoQ10
Mitochondria
PGC1α
Online Access:https://doi.org/10.1186/s12986-019-0418-8

Internet

https://doi.org/10.1186/s12986-019-0418-8

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