Hypoxia induced aggressiveness of prostate cancer cells is linked with deregulated expression of VEGF, IL-6 and miRNAs that are attenuated by CDF.

Tumor hypoxia with deregulated expression of hypoxia inducing factor (HIF) and its biological consequence leads to poor prognosis of patients diagnosed with solid tumors, resulting in higher mortality, suggesting that understanding of the molecular relationship of hypoxia with other cellular feature...

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Bibliographic Details
Main Authors: Bin Bao, Aamir Ahmad, Dejuan Kong, Shadan Ali, Asfar S Azmi, Yiwei Li, Sanjeev Banerjee, Subhash Padhye, Fazlul H Sarkar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3428287?pdf=render