Interdomain interactions regulate the localization of a lipid transfer protein at ER-PM contact sites

Interdomain interactions regulate the localization of a lipid transfer protein at ER-PM contact sites

During phospholipase C-β (PLC-β) signalling in Drosophila photoreceptors, the phosphatidylinositol transfer protein (PITP) RDGB, is required for lipid transfer at endoplasmic reticulum (ER)–plasma membrane (PM) contact sites (MCS). Depletion of RDGB or its mis-localization away from the ER–PM MCS re...

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Bibliographic Details
Main Authors: Bishal Basak, Harini Krishnan, Padinjat Raghu
Format: Article
Language:English
Published: The Company of Biologists 2021-03-01
Series:Biology Open
Subjects:
lipid transfer protein
membrane contact sites
inter-domain interactions
phosphoinositides
drosophila photoreceptors
Online Access:http://bio.biologists.org/content/10/3/bio057422

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