CircCDKN2B-AS1 interacts with IMP3 to stabilize hexokinase 2 mRNA and facilitate cervical squamous cell carcinoma aerobic glycolysis progression

CircCDKN2B-AS1 interacts with IMP3 to stabilize hexokinase 2 mRNA and facilitate cervical squamous cell carcinoma aerobic glycolysis progression

Abstract Background Circular RNAs (circRNAs) have been reported to play key roles in the development of various cancers. However, the biological functions and clinical significance of most circRNAs are still elusive. The purpose of this study was to explore the function and mechanism of a certain ci...

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Bibliographic Details
Main Authors: Yanan Zhang, Lu Zhao, Shizhou Yang, Yixuan Cen, Tingjia Zhu, Lingfang Wang, Lili Xia, Yuwan Liu, Jian Zou, Junfen Xu, Yang Li, Xiaodong Cheng, Weiguo Lu, Xinyu Wang, Xing Xie
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
CircRNA
CircCDKN2B-AS1
Cervical cancer
Aerobic glycolysis
IMP3
HK2
Online Access:https://doi.org/10.1186/s13046-020-01793-7

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