Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria

Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria

Show other versions (1)

Lamin A is a component of the nuclear lamina mutated in a group of human inherited disorders known as laminopathies. Among laminopathies, progeroid syndromes and lipodystrophies feature accumulation of prelamin A, the precursor protein which, in normal cells, undergoes a multi-step processing to yie...

Full description

Bibliographic Details
Main Authors:	G Lattanzi, NM Maraldi, C Vigouroux, G Novelli, M Caron, M Auclair, C Le Dour, MR D’Apice, D Camozzi, C Capanni, E Schena, M Magnani, V Fiori, S Dominici
Format:	Article
Language:	English
Published:	PAGEPress Publications 2009-03-01
Series:	European Journal of Histochemistry
Online Access:	http://ejh.pagepress.org/index.php/ejh/article/view/1232

Similar Items

Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria
by: S Dominici, et al.
Published: (2009-08-01)

Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria
by: V. Cenni, et al.
Published: (2011-10-01)

Erratum - Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria
by: V. Cenni, et al.
Published: (2013-12-01)

Prelamin A prenylation and the treatment of progeria1
by: Howard J. Worman
Published: (2010-02-01)

Thematic Review Series: Lipid Posttranslational Modifications. Prelamin A, Zmpste24, misshapen cell nuclei, and progeria—new evidence suggesting that protein farnesylation could be important for disease pathogenesis
by: Stephen G. Young, et al.
Published: (2005-12-01)

On the role of prelamin A in the heart
by: Brayson, Daniel James
Published: (2014)

Lamin A and Prelamin a Counteract Migration of Osteosarcoma Cells
by: Camilla Evangelisti, et al.
Published: (2020-03-01)

Progeria
by: Mohamed Riyaz S, et al.
Published: (2009-01-01)

Progeria
by: Utz S.R., et al.
Published: (2014-09-01)

Role of Zmpste24 in Prelamin A Maturation.
by: Corrigan, Douglas Paul
Published: (2005)

Nuclear envelope proteins and chromatin arrangement: a pathogenic mechanism for laminopathies
by: NM Maraldi, et al.
Published: (2009-06-01)

Living with Progeria
by: Stamsnijder Marjet
Published: (2010-10-01)

Prelaminated Supraclavicular Island Flap for Total Ear Reconstruction: A New Technique
by: Hélio R. N. Alves, MD, PhD, et al.
Published: (2020-05-01)

Hutchinson-Gilford Progeria Syndrome
by: Gopal G, et al.
Published: (2014-08-01)

Hutchinson-Gilford progeria syndrome
by: Zahoor Hussain Daraz, et al.
Published: (2017-06-01)

Immunocytochemistry of nuclear domains and Emery-Dreifuss muscular dystrophy pathophysiology
by: NM Maraldi, et al.
Published: (2009-06-01)

Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24.
by: Jemima Barrowman, et al.
Published: (2012-01-01)

Prelaminated temporal fascia free flap for reconstruction of the floor of the mouth
by: Vojko Didanovič, et al.
Published: (2011-03-01)

Some new results on a Lavrentieff phenomenon for problems of homogenization with constraints on the gradient
by: C. D'Apice, et al.
Published: (1999-05-01)

Hutchinson-Gilford progeria syndrome
by: Amar Singh Bhukya, et al.
Published: (2015-01-01)

Progeria and accelerated cardiovascular aging
by: Brandon K Walther, et al.
Published: (2018-01-01)

Tip of the Tongue Reconstruction with Prelaminated Fasciomucosal Radial Forearm Free Flap
by: Giorgio De Santis, MD, et al.
Published: (2020-12-01)

Prelaminated Gracilis Flap with Buccal Mucosal Graft for Salvage of Devastated Urethra
by: Dmitriy Nikolavsky
Published: (2015-01-01)

Our experiences in a patient with Progeria syndrome
by: M M Neema, et al.
Published: (2012-01-01)

Progeria in siblings: A rare case report
by: R Sowmiya, et al.
Published: (2011-01-01)

Multistage Ala Nasi Repair with an Expanded and Prelaminated Forehead Flap: A Case Report
by: Nina Dabrosin, MD, et al.
Published: (2021-09-01)

Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24
by: Sandy Y. Chang, et al.
Published: (2012-06-01)

Partial Ear Reconstruction with a Prelaminated Induced Expanded Radial Artery Flap
by: Federico Flaherty, MD, et al.
Published: (2021-02-01)

Defining substrate requirements for cleavage of farnesylated prelamin A by the integral membrane zinc metalloprotease ZMPSTE24.
by: Kaitlin M Wood, et al.
Published: (2020-01-01)

Nuclear damages and oxidative stress: new perspectives for laminopathies
by: G. Lattanzi, et al.
Published: (2012-10-01)

Stem cell aging in adult progeria
by: Hoi-Hung Cheung, et al.
Published: (2015-01-01)

Inguinal herniotomy in a patient with progeria
by: Tanvir K. Chowdhury, et al.
Published: (2020-06-01)

Vitiligo vulgaris in a patient of progeria
by: Bikash Ranjan Kar, et al.
Published: (2013-01-01)

An economic analysis of some factors associated with the international trade flows of frozen groundfish blocks
by: Paez, Maria Lucia D'Apice
Published: (2012)

Conservatively managed extradural haematoma in a child with progeria
by: Kapil Mohan Rajwani, et al.
Published: (2019-09-01)

Complex facial reconstruction based on 3D-models: prelamination cases and literature revision
by: Ana Francisca dos Santos Frias Correia
Published: (2021)

Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria
by: Shao H. Yang, et al.
Published: (2010-02-01)

Hutchinson-Gilford Progeria Syndrome: A Rare Genetic Disorder
by: Rajat G. Panigrahi, et al.
Published: (2013-01-01)

Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis
by: Elisa Di Pasquale, et al.
Published: (2019-04-01)

Small-Molecule Therapeutic Perspectives for the Treatment of Progeria
by: Jon Macicior, et al.
Published: (2021-07-01)