Non-motor Behavioral Alterations of PGC-1α-Deficient Mice – A Peculiar Phenotype With Slight Male Preponderance and No Apparent Progression

Non-motor Behavioral Alterations of PGC-1α-Deficient Mice – A Peculiar Phenotype With Slight Male Preponderance and No Apparent Progression

Dysfunction of peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1α) has been linked to various neurodegenerative and neuropsychiatric disorders; however, reports on psychic behavioral alterations on PGC-1α-deficient animals are sparse. The present study revisited prior observ...

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Bibliographic Details
Main Authors: Levente Szalardy, Mate F. Molnar, Denes Zadori, Edina K. Cseh, Gabor Veres, Gabor G. Kovacs, Laszlo Vecsei, Peter Klivenyi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
anxiety
behavior
depression
memory
peroxisome proliferator-activated receptor gamma coactivator
PGC-1α
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2018.00180/full

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