Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer

Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer

Abstract Background Salivary gland cancers are not sensitive to conventional radiotherapy or chemotherapy regimens. Therefore, the development of a new treatment strategy is of critical importance for improving the prognosis. We examined the expression of mesothelin molecules in salivary gland cance...

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Bibliographic Details
Main Authors: Yuji Makita, Naoki Kunii, Daiju Sakurai, Fumie Ihara, Shinichiro Motohashi, Akane Suzuki, Toshinori Nakayama, Yoshitaka Okamoto
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Adoptive immunotherapy
Chimeric antigen receptor
Cytotoxic T lymphocyte
Natural kiiler T-cells
Salivary gland cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-5179-7

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