Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3

Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3

Using a non-integrative reprogramming method, a human iPSC Line, ZZUNEUi002-A, was generated from a 22-year-old male patient with spinocerebellar ataxia type 3 /Machado-Joseph disease (SCA3/MJD). This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype. The iPSC line coul...

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Main Authors: Liting Wei, Jwei Zhang, Dingbang Chen, Li Feng, Chao Wu, Rui Wang, Xunhua Li
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120301999
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spelling doaj-b030f9eae56942a49d5bc5f56167f2832020-11-25T03:38:39ZengElsevierStem Cell Research1873-50612020-08-0147101898Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3Liting Wei0Jwei Zhang1Dingbang Chen2Li Feng3Chao Wu4Rui Wang5Xunhua Li6Department of Neurology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, Henan 467500, China; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 510052, ChinaDepartment of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 510052, China; Corresponding authors at: Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangzhou 510530, ChinaDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China; Corresponding authors at: Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.Using a non-integrative reprogramming method, a human iPSC Line, ZZUNEUi002-A, was generated from a 22-year-old male patient with spinocerebellar ataxia type 3 /Machado-Joseph disease (SCA3/MJD). This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype. The iPSC line could be used as a tool for mechanism researching and drug screening.http://www.sciencedirect.com/science/article/pii/S1873506120301999
collection DOAJ
language English
format Article
sources DOAJ
author Liting Wei
Jwei Zhang
Dingbang Chen
Li Feng
Chao Wu
Rui Wang
Xunhua Li
spellingShingle Liting Wei
Jwei Zhang
Dingbang Chen
Li Feng
Chao Wu
Rui Wang
Xunhua Li
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3
Stem Cell Research
author_facet Liting Wei
Jwei Zhang
Dingbang Chen
Li Feng
Chao Wu
Rui Wang
Xunhua Li
author_sort Liting Wei
title Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3
title_short Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3
title_full Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3
title_fullStr Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3
title_full_unstemmed Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3
title_sort generation of an integration-free induced pluripotent stem cell (ipsc) line (zzuneui002-a) from a patient with spinocerebellar ataxia type 3
publisher Elsevier
series Stem Cell Research
issn 1873-5061
publishDate 2020-08-01
description Using a non-integrative reprogramming method, a human iPSC Line, ZZUNEUi002-A, was generated from a 22-year-old male patient with spinocerebellar ataxia type 3 /Machado-Joseph disease (SCA3/MJD). This cell line shows pluripotency both in vitro and vivo, and has a normal karyotype. The iPSC line could be used as a tool for mechanism researching and drug screening.
url http://www.sciencedirect.com/science/article/pii/S1873506120301999
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