Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response

Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response

Antimicrobial peptides (AMPs) with antiviral activity (antiviral peptides: AVPs) have become a research hotspot and already show immense potential to become pharmaceutically available antiviral drugs. AVPs have exhibited huge potential in inhibiting viruses by targeting various stages of their life...

Full description

Bibliographic Details
Main Authors: Min Feng, Shigang Fei, Junming Xia, Vassiliki Labropoulou, Luc Swevers, Jingchen Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
antiviral peptides
antimicrobial peptides
insect
viruses
antiviral drugs
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02030/full
id doaj-b01b6f16272b4b859ad86653e904455a
record_format Article
spelling doaj-b01b6f16272b4b859ad86653e904455a2020-11-25T03:53:22ZengFrontiers Media S.A.Frontiers in Immunology1664-32242020-09-011110.3389/fimmu.2020.02030573073Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune ResponseMin Feng0Min Feng1Shigang Fei2Junming Xia3Vassiliki Labropoulou4Luc Swevers5Jingchen Sun6Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, ChinaInsect Molecular Genetics and Biotechnology, Institute of Biosciences and Applications, National Centre for Scientific Research Demokritos, Athens, GreeceGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, ChinaInsect Molecular Genetics and Biotechnology, Institute of Biosciences and Applications, National Centre for Scientific Research Demokritos, Athens, GreeceInsect Molecular Genetics and Biotechnology, Institute of Biosciences and Applications, National Centre for Scientific Research Demokritos, Athens, GreeceGuangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, ChinaAntimicrobial peptides (AMPs) with antiviral activity (antiviral peptides: AVPs) have become a research hotspot and already show immense potential to become pharmaceutically available antiviral drugs. AVPs have exhibited huge potential in inhibiting viruses by targeting various stages of their life cycle. Insects are the most speciose group of animals that inhabit almost all ecosystems and habitats on the land and are a rich source of natural AMPs. However, insect AVP mining, functional research, and drug development are still in their infancy. This review aims to summarize the currently validated insect AVPs, explore potential new insect AVPs and to discuss their possible mechanism of synthesis and action, with a view to providing clues to unravel the mechanisms of insect antiviral immunity and to develop insect AVP-derived antiviral drugs.https://www.frontiersin.org/article/10.3389/fimmu.2020.02030/fullantiviral peptidesantimicrobial peptidesinsectvirusesantiviral drugs
collection DOAJ
language English
format Article
sources DOAJ
author Min Feng
Min Feng
Shigang Fei
Junming Xia
Vassiliki Labropoulou
Luc Swevers
Jingchen Sun
spellingShingle Min Feng
Min Feng
Shigang Fei
Junming Xia
Vassiliki Labropoulou
Luc Swevers
Jingchen Sun
Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response
Frontiers in Immunology
antiviral peptides
antimicrobial peptides
insect
viruses
antiviral drugs
author_facet Min Feng
Min Feng
Shigang Fei
Junming Xia
Vassiliki Labropoulou
Luc Swevers
Jingchen Sun
author_sort Min Feng
title Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response
title_short Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response
title_full Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response
title_fullStr Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response
title_full_unstemmed Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response
title_sort antimicrobial peptides as potential antiviral factors in insect antiviral immune response
publisher Frontiers Media S.A.
series Frontiers in Immunology
issn 1664-3224
publishDate 2020-09-01
description Antimicrobial peptides (AMPs) with antiviral activity (antiviral peptides: AVPs) have become a research hotspot and already show immense potential to become pharmaceutically available antiviral drugs. AVPs have exhibited huge potential in inhibiting viruses by targeting various stages of their life cycle. Insects are the most speciose group of animals that inhabit almost all ecosystems and habitats on the land and are a rich source of natural AMPs. However, insect AVP mining, functional research, and drug development are still in their infancy. This review aims to summarize the currently validated insect AVPs, explore potential new insect AVPs and to discuss their possible mechanism of synthesis and action, with a view to providing clues to unravel the mechanisms of insect antiviral immunity and to develop insect AVP-derived antiviral drugs.
topic antiviral peptides
antimicrobial peptides
insect
viruses
antiviral drugs
url https://www.frontiersin.org/article/10.3389/fimmu.2020.02030/full
work_keys_str_mv AT minfeng antimicrobialpeptidesaspotentialantiviralfactorsininsectantiviralimmuneresponse
AT minfeng antimicrobialpeptidesaspotentialantiviralfactorsininsectantiviralimmuneresponse
AT shigangfei antimicrobialpeptidesaspotentialantiviralfactorsininsectantiviralimmuneresponse
AT junmingxia antimicrobialpeptidesaspotentialantiviralfactorsininsectantiviralimmuneresponse
AT vassilikilabropoulou antimicrobialpeptidesaspotentialantiviralfactorsininsectantiviralimmuneresponse
AT lucswevers antimicrobialpeptidesaspotentialantiviralfactorsininsectantiviralimmuneresponse
AT jingchensun antimicrobialpeptidesaspotentialantiviralfactorsininsectantiviralimmuneresponse
_version_ 1724478476482772992

Similar Items