Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line.

Clitocine reversal of P-glycoprotein associated multi-drug resistance through down-regulation of transcription factor NF-κB in R-HepG2 cell line.

Multidrug resistance (MDR) is one of the major reasons for failure in cancer chemotherapy and its suppression may increase the efficacy of therapy. The human multidrug resistance 1 (MDR1) gene encodes the plasma membrane P-glycoprotein (P-gp) that pumps various anti-cancer agents out of the cancer c...

Full description

Bibliographic Details
Main Authors: Jianguo Sun, Chilam Au Yeung, Ngai Na Co, Tsun Yee Tsang, Esmond Yau, Kewang Luo, Ping Wu, Judy Chan Yuet Wa, Kwok-Pui Fung, Tim-Tak Kwok, Feiyan Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22927901/pdf/?tool=EBI

Similar Items

Similar Items