HIV-1 Subtypes and 5’LTR-Leader Sequence Variants Correlate with Seroconversion Status in Pumwani Sex Worker Cohort

HIV-1 Subtypes and 5’LTR-Leader Sequence Variants Correlate with Seroconversion Status in Pumwani Sex Worker Cohort

Within the Pumwani sex worker cohort, a subgroup remains seronegative, despite frequent exposure to HIV-1; some of them seroconverted several years later. This study attempts to identify viral variations in 5’LTR-leader sequences (5’LTR-LS) that might contribute to the late seroconversion. The 5’LTR...

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Bibliographic Details
Main Authors: Raghavan Sampathkumar, Joel Scott-Herridge, Binhua Liang, Joshua Kimani, Francis A. Plummer, Ma Luo
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Viruses
Subjects:
HIV/AIDS
seroconversion
5’LTR-leader sequence
genetic diversity
primer binding site sequences
splicing donor sequences
packaging signal
HIV subtypes
Online Access:https://www.mdpi.com/1999-4915/10/1/4

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