Novel Methodology for Rapid Detection of KRAS Mutation Using PNA-LNA Mediated Loop-Mediated Isothermal Amplification.

Novel Methodology for Rapid Detection of KRAS Mutation Using PNA-LNA Mediated Loop-Mediated Isothermal Amplification.

Detecting point mutation of human cancer cells quickly and accurately is gaining in importance for pathological diagnosis and choice of therapeutic approach. In the present study, we present novel methodology, peptide nucleic acid-locked nucleic acid mediated loop-mediated isothermal amplification (...

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Bibliographic Details
Main Authors: Masahiro Itonaga, Ibu Matsuzaki, Kenji Warigaya, Takaaki Tamura, Yuki Shimizu, Masakazu Fujimoto, Fumiyoshi Kojima, Masao Ichinose, Shin-Ichi Murata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4801409?pdf=render

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http://europepmc.org/articles/PMC4801409?pdf=render

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