Sulfatases, in Particular Sulf1, Are Important for the Integrity of the Glomerular Filtration Barrier in Zebrafish

The 6-O-endosulfatases (sulfs) are important enzymatic components involved in the regulation of heparan sulfate by altering the sulfatation pattern. Specifically in the kidney, sulfs have been implicated in the glomerular podocyte-endothelial cell crosstalk and in the preservation of the glomerular...

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Bibliographic Details
Main Authors: Heiko Schenk, Anna Masseli, Patricia Schroder, Patricia Bolaños-Palmieri, Michaela Beese, Jan Hegermann, Jan Hinrich Bräsen, Hermann Haller
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2019/4508048