Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice.

Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice.

Aquaporin-4 (AQP4) plays an important role in regulating water exchange across the blood-brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice (AQP4-KO) have reported considerable protection from brain edema induced by acute water intoxication and ischemic strok...

Full description

Bibliographic Details
Main Authors: Yifan Zhang, Kui Xu, Yuchi Liu, Bernadette O Erokwu, Pan Zhao, Chris A Flask, Ciro Ramos-Estebanez, George W Farr, Joseph C LaManna, Walter F Boron, Xin Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218415

Internet

https://doi.org/10.1371/journal.pone.0218415

Similar Items