A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensis
A novel 18-nor-clerodane diterpenoid named sagitone (1) was isolated from the 95% ethanol extract of dry roots of Tinospora sagittata var. yunnanensis together with the five known diterpenoids columbin (2), palmatoside C (3), fibleucin (4), tinophylloloside (5) and epitinophylloloside (6). The struc...
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-11-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/15/11/8360/ |
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doaj-afcf9b3e0cfe4c8cb18833028d31cb392020-11-24T20:56:21ZengMDPI AGMolecules1420-30492010-11-0115118360836510.3390/molecules15118360A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensisHui LiangYan YinYun DaiXiang-Zhong HuangJun-Ming GuoGuang-Miao FuChun-Mei ChengA novel 18-nor-clerodane diterpenoid named sagitone (1) was isolated from the 95% ethanol extract of dry roots of Tinospora sagittata var. yunnanensis together with the five known diterpenoids columbin (2), palmatoside C (3), fibleucin (4), tinophylloloside (5) and epitinophylloloside (6). The structure of the new compound 1 was determined based on MS, IR, 1D and 2D NMR spectral data. The compounds 1~6 did not show significant cytotoxic activity against cancer cell lines K562 and HL-60. http://www.mdpi.com/1420-3049/15/11/8360/Tinospora sagittata var. Yunnanensisclerodane diterpenoidsagitonecytotoxic activity |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Hui Liang Yan Yin Yun Dai Xiang-Zhong Huang Jun-Ming Guo Guang-Miao Fu Chun-Mei Cheng |
| spellingShingle |
Hui Liang Yan Yin Yun Dai Xiang-Zhong Huang Jun-Ming Guo Guang-Miao Fu Chun-Mei Cheng A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensis Molecules Tinospora sagittata var. Yunnanensis clerodane diterpenoid sagitone cytotoxic activity |
| author_facet |
Hui Liang Yan Yin Yun Dai Xiang-Zhong Huang Jun-Ming Guo Guang-Miao Fu Chun-Mei Cheng |
| author_sort |
Hui Liang |
| title |
A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensis |
| title_short |
A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensis |
| title_full |
A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensis |
| title_fullStr |
A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensis |
| title_full_unstemmed |
A Novel 18-Norclerodane Diterpenoid from the Roots of Tinospora sagittata var. yunnanensis |
| title_sort |
novel 18-norclerodane diterpenoid from the roots of tinospora sagittata var. yunnanensis |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2010-11-01 |
| description |
A novel 18-nor-clerodane diterpenoid named sagitone (1) was isolated from the 95% ethanol extract of dry roots of Tinospora sagittata var. yunnanensis together with the five known diterpenoids columbin (2), palmatoside C (3), fibleucin (4), tinophylloloside (5) and epitinophylloloside (6). The structure of the new compound 1 was determined based on MS, IR, 1D and 2D NMR spectral data. The compounds 1~6 did not show significant cytotoxic activity against cancer cell lines K562 and HL-60. |
| topic |
Tinospora sagittata var. Yunnanensis clerodane diterpenoid sagitone cytotoxic activity |
| url |
http://www.mdpi.com/1420-3049/15/11/8360/ |
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