Autoimmune blistering disorders in the setting of human immunodeficiency virus infection

The interplay between immune dysfunction and human immunodeficiency virus (HIV) is complex. Reports of autoimmune disorders including autoimmune bullous disorders (AIBDs) have been increasing in prevalence in the HIV population since the introduction of highly active antiretroviral therapy in 1995....

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Bibliographic Details
Main Authors: M.S. Min, MD, MSci, E. Damstetter, MD, A.Y.Y. Chen, MD
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:International Journal of Women's Dermatology
Online Access:http://www.sciencedirect.com/science/article/pii/S235264751830011X
Description
Summary:The interplay between immune dysfunction and human immunodeficiency virus (HIV) is complex. Reports of autoimmune disorders including autoimmune bullous disorders (AIBDs) have been increasing in prevalence in the HIV population since the introduction of highly active antiretroviral therapy in 1995. We offer a literature review of clinical experiences in various AIBDs with particular emphasis on therapeutic management as well as a brief overview of the mechanisms that explain the relationship between AIBD and HIV. Because immunosuppressants are first-line therapies for AIBD treatment, careful consideration is warranted when considering management in the HIV population. Keywords: Autoimmune blistering disorder, human immunodeficiency virus, acquired immune deficiency syndrome, pemphigus, pemphigoid, medical dermatology, antiretroviral therapy
ISSN:2352-6475