Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis

Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis

Tumor cells that acquire metastatic potential have developed resistance to anoikis, a cell death process, after detachment from their primary site to the second organ. In this study, we investigated the molecular mechanisms of a novel marine bacterial polysaccharide EPS11 which exerts its cytotoxic...

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Bibliographic Details
Main Authors: Ruobing Cao, Weihua Jin, Yeqi Shan, Ju Wang, Ge Liu, Shan Kuang, Chaomin Sun
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Marine Drugs
Subjects:
polysaccharide
cancer
filiform structures
βIII-tubulin
anoikis
adhesion
Online Access:http://www.mdpi.com/1660-3397/16/3/85

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