Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

Abstract Background Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in dehydroepiandrosterone (DHEA)-induce...

Full description

Bibliographic Details
Main Authors: Ya-Li Yang, Li-Feng Sun, Yan Yu, Tian-Xia Xiao, Bao-Bei Wang, Pei-Gen Ren, Hui-Ru Tang, Jian V. Zhang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
GPR1
Hyperandrogenism
Steroidogenesis
Estradiol
Online Access:http://link.springer.com/article/10.1186/s12958-018-0363-9

Internet

http://link.springer.com/article/10.1186/s12958-018-0363-9

Similar Items