A data-driven approach for studying the role of body mass in multiple diseases: a phenome-wide registry-based case-control study in the UK Biobank

Summary: Background: Mendelian randomisation allows for the testing of causal effects in situations where clinical trials are challenging to do. In this hypothesis-free, data-driven phenome-wide association study (PheWAS), we sought to assess possible associations of high body-mass index (BMI) with...

Full description

Bibliographic Details
Main Authors: Elina Hyppönen, ProfPhD, Anwar Mulugeta, MSc, Ang Zhou, PhD, Vimaleswaran Karani Santhanakrishnan, PhD
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:The Lancet: Digital Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2589750019300287