Anal adenocarcinoma: case report, literature review and comparative survival analysis

Anal adenocarcinoma: case report, literature review and comparative survival analysis

Introduction Anal adenocarcinoma is a rare malignancy with a poor prognosis.Methods We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among i...

Full description

Bibliographic Details
Main Authors: Jocelyn B Chandler, Anil B Nagar, Cynthia J Tsay, Thomas Pointer, Petr Protiva
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/8/1/e000661.full
id doaj-afbb08a8c5694d62b9fc530b3eaeaa66
record_format Article
spelling doaj-afbb08a8c5694d62b9fc530b3eaeaa662021-10-10T22:00:05ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742021-05-018110.1136/bmjgast-2021-000661Anal adenocarcinoma: case report, literature review and comparative survival analysisJocelyn B Chandler0Anil B Nagar1Cynthia J Tsay2Thomas Pointer3Petr Protiva4Pathology, Yale School of Medicine, New Haven, Connecticut, USAMedicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USAMedicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USAYale University Undergraduate Program, New Haven, Connecticut, USAMedicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut, USAIntroduction Anal adenocarcinoma is a rare malignancy with a poor prognosis.Methods We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among individuals>20 years old comparing anal and rectal cancers.Results Survival analysis showed that anal adenocarcinoma is associated with worse outcomes compared with rectal adenocarcinoma and anal squamous cell carcinoma.Discussion This case and survival data illustrate the importance of prompt investigation of symptoms irrespective of colorectal cancer screening status with careful attention to examination of the anal area.https://bmjopengastro.bmj.com/content/8/1/e000661.full
collection DOAJ
language English
format Article
sources DOAJ
author Jocelyn B Chandler
Anil B Nagar
Cynthia J Tsay
Thomas Pointer
Petr Protiva
spellingShingle Jocelyn B Chandler
Anil B Nagar
Cynthia J Tsay
Thomas Pointer
Petr Protiva
Anal adenocarcinoma: case report, literature review and comparative survival analysis
BMJ Open Gastroenterology
author_facet Jocelyn B Chandler
Anil B Nagar
Cynthia J Tsay
Thomas Pointer
Petr Protiva
author_sort Jocelyn B Chandler
title Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_short Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_full Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_fullStr Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_full_unstemmed Anal adenocarcinoma: case report, literature review and comparative survival analysis
title_sort anal adenocarcinoma: case report, literature review and comparative survival analysis
publisher BMJ Publishing Group
series BMJ Open Gastroenterology
issn 2054-4774
publishDate 2021-05-01
description Introduction Anal adenocarcinoma is a rare malignancy with a poor prognosis.Methods We present a case of rare anal adenocarcinoma in a patient with normal screening colonoscopy. Using the Surveillance, Epidemiology and End Result database between 2000 and 2016, we performed survival analysis among individuals>20 years old comparing anal and rectal cancers.Results Survival analysis showed that anal adenocarcinoma is associated with worse outcomes compared with rectal adenocarcinoma and anal squamous cell carcinoma.Discussion This case and survival data illustrate the importance of prompt investigation of symptoms irrespective of colorectal cancer screening status with careful attention to examination of the anal area.
url https://bmjopengastro.bmj.com/content/8/1/e000661.full
work_keys_str_mv AT jocelynbchandler analadenocarcinomacasereportliteraturereviewandcomparativesurvivalanalysis
AT anilbnagar analadenocarcinomacasereportliteraturereviewandcomparativesurvivalanalysis
AT cynthiajtsay analadenocarcinomacasereportliteraturereviewandcomparativesurvivalanalysis
AT thomaspointer analadenocarcinomacasereportliteraturereviewandcomparativesurvivalanalysis
AT petrprotiva analadenocarcinomacasereportliteraturereviewandcomparativesurvivalanalysis
_version_ 1716829297238343680

Similar Items