Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells

Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells

The production of recombinant proteins in bioreactors requires real-time process monitoring and control to increase process efficiency and to meet the requirements for a comprehensive audit trail. The combination of optical near-infrared turbidity sensors and dielectric spectroscopy provides diverse...

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Bibliographic Details
Main Authors: Jan Zitzmann, Tobias Weidner, Gerrit Eichner, Denise Salzig, Peter Czermak
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Sensors
Subjects:
dielectric spectroscopy
impedance spectroscopy
optical density measurements
process monitoring
process control
fermentation
recombinant protein production
Drosophila S2
Online Access:http://www.mdpi.com/1424-8220/18/3/900

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http://www.mdpi.com/1424-8220/18/3/900

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