Ikbkap/Elp1 deficiency causes male infertility by disrupting meiotic progression.
Mouse Ikbkap gene encodes IKAP--one of the core subunits of Elongator--and is thought to be involved in transcription. However, the biological function of IKAP, particularly within the context of an animal model, remains poorly characterized. We used a loss-of-function approach in mice to demonstrat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-05-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3662645?pdf=render |