Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: Role of β-catenin/hnRNPK signaling

Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: Role of β-catenin/hnRNPK signaling

In the newborn, alveolarization continues postnatally and can be disrupted by hyperoxia, leading to long-lasting consequences on lung function. We wanted to better understand the role of heme oxygenase (HO)-1, the inducible form of the rate-limiting enzyme in heme degradation, in neonatal hyperoxic...

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Bibliographic Details
Main Authors: Guang Yang, Chhanda Biswasa, Qing Sara Lin, Ping La, Fumihiko Namba, Tiangang Zhuang, Manasa Muthu, Phyllis A. Dennery
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Heme oxygenase-1
Neonatal hyperoxic lung injury and repair
β-catenin/hnRNPK
DNA damage and repair
Cell proliferation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000347

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http://www.sciencedirect.com/science/article/pii/S2213231713000347

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