Attenuating MKRN1 E3 ligase-mediated AMPKα suppression increases tolerance against metabolic stresses in mice

Attenuating MKRN1 E3 ligase-mediated AMPKα suppression increases tolerance against metabolic stresses in mice

The 5′ adenosine monophosphate-activated protein kinase (AMPK) is an essential energy sensor in the cell, which, at low energy levels, instigates the cellular energy-generating systems along with suppression of the anabolic signaling pathways. The activation of AMPK through phosphorylation is a well...

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Bibliographic Details
Main Authors: Hyunji Han, Sehyun Chae, Daehee Hwang, Jaewhan Song
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-10-01
Series:Cell Stress
Subjects:
AMPK
MKRN1
metabolic syndrome
obesity
diabetes
Online Access:http://www.cell-stress.com/researcharticles/attenuating-mkrn1-e3-ligase-mediated-ampk%CE%B1-suppression-increases-tolerance-against-metabolic-stresses-in-mice/

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