CRISPR interference directs strand specific spacer acquisition.

<h4>Background</h4>CRISPR/Cas is a widespread adaptive immune system in prokaryotes. This system integrates short stretches of DNA derived from invading nucleic acids into genomic CRISPR loci, which function as memory of previously encountered invaders. In Escherichia coli, transcripts o...

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Bibliographic Details
Main Authors: Daan C Swarts, Cas Mosterd, Mark W J van Passel, Stan J J Brouns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22558257/?tool=EBI

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