Classification of pediatric gliomas based on immunological profiling: implications for immunotherapy strategies

Classification of pediatric gliomas based on immunological profiling: implications for immunotherapy strategies

Pediatric gliomas (PGs) are the most common brain tumors in children and the leading cause of childhood cancer-related death. The understanding of the immune microenvironment is essential for developing effective antitumor immunotherapies. Transcriptomic data from 495 PGs were analyzed in this study...

Full description

Bibliographic Details
Main Authors: Zihao Wang, Xiaopeng Guo, Lu Gao, Yu Wang, Yi Guo, Bing Xing, Wenbin Ma
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
pediatric glioma
immune classification
overall survival
immunotherapy responsiveness
tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301868

Internet

http://www.sciencedirect.com/science/article/pii/S2372770520301868

Similar Items