Pegylated Interferon α-2a Triggers NK-Cell Functionality and Specific T-Cell Responses in Patients with Chronic HBV Infection without HBsAg Seroconversion.

Pegylated Interferon α-2a Triggers NK-Cell Functionality and Specific T-Cell Responses in Patients with Chronic HBV Infection without HBsAg Seroconversion.

Pegylated interferon α-2a (Peg-IFN-α) represents a therapeutic alternative to the prolonged use of nucleos(t)ide analog (NA) in chronic hepatitis B (CHB) infection. The mechanisms leading to a positive clinical outcome remain unclear. As immune responses are critical for virus control, we investigat...

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Main Authors: Juliana Bruder Costa, Tania Dufeu-Duchesne, Vincent Leroy, Inga Bertucci, Magali Bouvier-Alias, Noelle Pouget, Ophelie Brevot-Lutton, Marc Bourliere, Fabien Zoulim, Joel Plumas, Caroline Aspord, ANRS HB06 PEGAN study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4922676?pdf=render

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