The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception

The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception

Summary: Candida albicans infection can cause skin, vulvar, or oral pain. Despite the obvious algesic activity of C. albicans, the molecular mechanisms of fungal nociception remain largely unknown. Here we show that the C. albicans-specific signaling pathway led to severe mechanical allodynia. We di...

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Bibliographic Details
Main Authors: Kenta Maruyama, Yasunori Takayama, Erika Sugisawa, Yu Yamanoi, Takashi Yokawa, Takeshi Kondo, Ken-ichi Ishibashi, Bikash Ranjan Sahoo, Naoki Takemura, Yuki Mori, Hisashi Kanemaru, Yutaro Kumagai, Mikaël M. Martino, Yoshichika Yoshioka, Hisao Nishijo, Hiroki Tanaka, Atsushi Sasaki, Naohito Ohno, Yoichiro Iwakura, Yoshinori Moriyama, Masatoshi Nomura, Shizuo Akira, Makoto Tominaga
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218301196

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