Elevation of HO-1 Expression Mitigates Intestinal Ischemia-Reperfusion Injury and Restores Tight Junction Function in a Rat Liver Transplantation Model

Elevation of HO-1 Expression Mitigates Intestinal Ischemia-Reperfusion Injury and Restores Tight Junction Function in a Rat Liver Transplantation Model

Aims. This study was aimed at investigating whether elevation of heme oxygenase-1 (HO-1) expression could lead to restoring intestinal tight junction (TJ) function in a rat liver transplantation model. Methods. Intestinal mucosa injury was induced by orthotopic autologous liver transplantation (OALT...

Full description

Bibliographic Details
Main Authors:	Xinjin Chi, Weifeng Yao, Hua Xia, Yi Jin, Xi Li, Jun Cai, Ziqing Hei
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2015/986075

Similar Items

Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation
by: Yihan Zhang, et al.
Published: (2016-01-01)

Oxidative Stress and Inflammation Interaction in Ischemia Reperfusion Injury: Role of Programmed Cell Death
by: Weifeng Yao, et al.
Published: (2019-01-01)

Autophagy and tight junction proteins in the intestine and intestinal diseases
by: Chien-An A. Hu, et al.
Published: (2015-09-01)

Electroacupuncture Treatment Improves Neurological Function Associated with Regulation of Tight Junction Proteins in Rats with Cerebral Ischemia Reperfusion Injury
by: Ya-min Zhang, et al.
Published: (2014-01-01)

Activating AMPK to Restore Tight Junction Assembly in Intestinal Epithelium and to Attenuate Experimental Colitis by Metformin
by: Lu Chen, et al.
Published: (2018-07-01)

The HO-1-expressing bone mesenchymal stem cells protects intestine from ischemia and reperfusion injury
by: Xue-Tao Yan, et al.
Published: (2019-07-01)

The Mechanism of Sevoflurane Preconditioning-Induced Protections against Small Intestinal Ischemia Reperfusion Injury Is Independent of Mast Cell in Rats
by: Xiaoliang Gan, et al.
Published: (2013-01-01)

Downregulation of Lung Toll-Like Receptor 4 Could Effectively Attenuate Liver Transplantation-Induced Pulmonary Damage at the Early Stage of Reperfusion
by: Xinjin Chi, et al.
Published: (2015-01-01)

Corrigendum to “Electroacupuncture Treatment Improves Neurological Function Associated with Regulation of Tight Junction Proteins in Rats with Cerebral Ischemia Reperfusion Injury”
by: Ya-Min Zhang, et al.
Published: (2015-01-01)

Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner
by: Xue Han, et al.
Published: (2016-01-01)

Imidacloprid increases intestinal permeability by disrupting tight junctions
by: Guo-Ping Zhao, et al.
Published: (2021-10-01)

Partial Enteral Nutrition Mitigated Ischemia/Reperfusion-Induced Damage of Rat Small Intestinal Barrier
by: Chao Wu, et al.
Published: (2016-08-01)

Ischemia–Reperfusion Injury in Lung Transplantation
by: Toyofumi Fengshi Chen-Yoshikawa
Published: (2021-05-01)

Intestinal tight junctions are severely altered in NEC preterm neonates
by: Amir Bein, et al.
Published: (2018-10-01)

Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects
by: Mian Ge, et al.
Published: (2017-01-01)

Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation
by: Xiaoliang Gan, et al.
Published: (2015-01-01)

Contribution of myeloid HO-1 to the modulation of renal ischemia-reperfusion injury: Effect of myeloid HO-1 induction with hemin as a preemptive treatment strategy against renal ischemia-reperfusion injury
by: Rossi, Maxime
Published: (2020)

Corrigendum to “Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation”
by: Xiaoliang Gan, et al.
Published: (2017-01-01)

Prolylcarboxypeptidase Mitigates Myocardial Ischemia/Reperfusion Injury by Stabilizing Mitophagy
by: Panpan Hao, et al.
Published: (2020-10-01)

13-Methyltetradecanoic acid mitigates cerebral ischemia/reperfusion injury
by: Juan Yu, et al.
Published: (2016-01-01)

Tight Junctions as a Key for Pathogens Invasion in Intestinal Epithelial Cells
by: Tracy Paradis, et al.
Published: (2021-03-01)

Effect of Perfluorooctanoic Acid on the Epigenetic and Tight Junction Genes of the Mouse Intestine
by: Faizan Rashid, et al.
Published: (2020-08-01)

The Integral Role of Tight Junction Proteins in the Repair of Injured Intestinal Epithelium
by: Zachary M. Slifer, et al.
Published: (2020-02-01)

Intestinal fluid absorption in anadromous salmonids: importance of tight junctions and aquaporins
by: Kristina eSundell, et al.
Published: (2012-09-01)

Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases
by: Sung Hee Lee
Published: (2015-01-01)

Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals
by: Bonggi Lee, et al.
Published: (2018-01-01)

Donor Preconditioning with Inhaled Sevoflurane Mitigates the Effects of Ischemia-Reperfusion Injury in a Swine Model of Lung Transplantation
by: Alessandro Bertani, et al.
Published: (2021-01-01)

Intestinal P-glycoprotein Expression is Multimodally Regulated by Intestinal Ischemia-Reperfusion
by: Yusuke Terada, et al.
Published: (2014-06-01)

Protective effects of HO‐1 pathway on lung injury subsequent to limb ischemia reperfusion
by: Yan‐Yan Li, et al.
Published: (2019-07-01)

Postconditioning attenuates acute intestinal ischemia–reperfusion injury
by: Ilker Sengul, et al.
Published: (2013-03-01)

Intravenous Anesthetics Enhance the Ability of Human Bone Marrow-Derived Mesenchymal Stem Cells to Alleviate Hepatic Ischemia-Reperfusion Injury in a Receptor-Dependent Manner
by: Jiayu Feng, et al.
Published: (2018-05-01)

Mangiferin Mitigates Gastric Ulcer in Ischemia/ Reperfused Rats: Involvement of PPAR-γ, NF-κB and Nrf2/HO-1 Signaling Pathways.
by: Magdy Mahmoud-Awny, et al.
Published: (2015-01-01)

Propofol Activation of the Nrf2 Pathway Is Associated with Amelioration of Acute Lung Injury in a Rat Liver Transplantation Model
by: Weifeng Yao, et al.
Published: (2014-01-01)

Toll-Like Receptors in Hepatic Ischemia/Reperfusion and Transplantation
by: John Evankovich, et al.
Published: (2010-01-01)

Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses
by: O. Inczefi, et al.
Published: (2020-01-01)

Orexigenic hormone ghrelin attenuates local and remote organ injury after intestinal ischemia-reperfusion.
by: Rongqian Wu, et al.
Published: (2008-04-01)

The protective role of IL-1Ra on intestinal ischemia reperfusion injury by anti-oxidative stress via Nrf2/HO-1 pathway in rat
by: Chen Jin, et al.
Published: (2019-02-01)

Sesamin Protects against and Ameliorates Rat Intestinal Ischemia/Reperfusion Injury with Involvement of Activating Nrf2/HO-1/NQO1 Signaling Pathway
by: Yilin Wang, et al.
Published: (2021-01-01)

Dynamic alteration of the colonic microbiota in intestinal ischemia-reperfusion injury.
by: Fan Wang, et al.
Published: (2012-01-01)

Pathways of complement activation following intestinal ischemia-reperfusion in macaque
by: Lantao Xu, et al.
Published: (2012-01-01)