Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic Phenotypes

Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic Phenotypes

The epithelial-mesenchymal transition (EMT) is a highly conserved program necessary for orchestrating distant cell migration during embryonic development. Multiple studies in cancer have demonstrated a critical role for EMT during the initial stages of tumorigenesis and later during tumor invasion....

Full description

Bibliographic Details
Main Authors: Kekoa eTaparra, Phuoc eTran, Natasha eZachara
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Oncology
Subjects:
Glycoproteins
Glycosylation
Metabolism
senescence
O-GlcNAc
O-GlcNAcylation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00085/full

Similar Items

Similar Items