Decorin Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Induces Macrophage Polarization via CD44 to Repair Hyperoxic Lung Injury

Decorin Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Induces Macrophage Polarization via CD44 to Repair Hyperoxic Lung Injury

Bronchopulmonary dysplasia (BPD), caused by hyperoxia in newborns and infants, results in lung damage and abnormal pulmonary function. However, the current treatments for BPD are steroidal and pharmacological therapies, which cause neurodevelopmental impairment. Treatment with umbilical cord blood-d...

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Bibliographic Details
Main Authors: Ji Hye Kwon, Miyeon Kim, Yun Kyung Bae, Gee-Hye Kim, Soo Jin Choi, Wonil Oh, Soyoun Um, Hye Jin Jin
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
bronchopulmonary dysplasia
mesenchymal stem cell
macrophage polarization
decorin
cd44
Online Access:https://www.mdpi.com/1422-0067/20/19/4815

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