The effect on intracytoplasmic sperm injection outcome of genotype, male germ cell stage and freeze-thawing in mice.

BACKGROUND: Intracytoplasmic sperm injection (ICSI) has been widely used to study the mechanisms of mammalian fertilization and to rescue male-factor infertility in humans and animals. However, very few systematic analyses have been conducted to define factors affecting the efficiency of ICSI. In th...

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Bibliographic Details
Main Authors: Narumi Ogonuki, Manami Mori, Akie Shinmen, Kimiko Inoue, Keiji Mochida, Akihiko Ohta, Atsuo Ogura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2884038?pdf=render