All Paired Up with No Place to Go: Pairing, Synapsis, and DSB Formation in a Balancer Heterozygote.
The multiply inverted X chromosome balancer FM7 strongly suppresses, or eliminates, the occurrence of crossing over when heterozygous with a normal sequence homolog. We have utilized the LacI-GFP: lacO system to visualize the effects of FM7 on meiotic pairing, synapsis, and double-strand break forma...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2005-11-01
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Series: | PLoS Genetics |
Online Access: | http://dx.doi.org/10.1371/journal.pgen.0010067 |