All Paired Up with No Place to Go: Pairing, Synapsis, and DSB Formation in a Balancer Heterozygote.

The multiply inverted X chromosome balancer FM7 strongly suppresses, or eliminates, the occurrence of crossing over when heterozygous with a normal sequence homolog. We have utilized the LacI-GFP: lacO system to visualize the effects of FM7 on meiotic pairing, synapsis, and double-strand break forma...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-11-01
Series:PLoS Genetics
Online Access:http://dx.doi.org/10.1371/journal.pgen.0010067