An integrated, temporal study of the behavioural, electrophysiological and neuropathological consequences of murine prion disease

We have conducted an integrated study of ME7 prion disease by examining the electrophysiological and neuropathological features of hippocampal slices from behaviourally characterised C57Bl/6J mice 12, 14, 16, 18, 20 and 24 weeks after intracerebral micro-injection of ME7 or normal brain homogenate.W...

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Bibliographic Details
Main Authors: Z. Chiti, O.M. Knutsen, S. Betmouni, J.R.T. Greene
Format: Article
Language:English
Published: Elsevier 2006-05-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105003335